In 1985, Caritas Francis Hsu College was founded, with its campus located at 11 Caine Road. In 1990, the college obtained approval from the Hong Kong government to offer post-secondary education.

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In its early years, Caritas Francis Hsu College primarily offered pre-university courses and 2-year diploma programs in subjects such as accounting, management studies, and computer science. It registered as an Approved Post Secondary College in 2001 under the CAP.320.